So, what is the Melengestrol Acetate? Melengestrol acetate is a pregnane. It is approved for use as a growth promoter in livestock, including beef cattle, in the United States. Its use is not approved in the European Union or Canada. The steroids trenbolone acetate (TBA) and melengestrol acetate (MGA) are licensed as growth promoters for farm animals in several meat-exporting countries. Melengestrol acetate is fed for the duration of the fattening and finishing period, usually for 90-150 days.
Melengestrol acetate has not previously been evaluated by the Committee. Four heifers were fed diets containing melengestrol acetate at a dose of approximately 0.5 mg/head per day for 4 months. Three animals then received 3H-melengestrol acetate for 21 days, and one received 14C-labelled material for 7 days while housed in a metabolism stall. The radiolabelled compounds were administered in gelatine capsules. Urine obtained through a catheter and faeces were collected and assayed for radiolabel.